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The Drug-Induced Respiratory Disease Website

Philippe Camus, M.D.

Dijon, France

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Imatinib

3

XV.a Path: NSIP-cellular pattern (see also Ia, Ib)

1
Last update : 27/08/2013
 
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Identify causative drugs
Diagnosing DIRD
1
Drug and radiation history
2
Drug singularity - Correct identification of the drug
3
Consistent timing of exposure v. onset of symptoms
4
Clinical, imaging, BAL, pathological pattern consistent with the specific drug
5
Careful exlusion of another cause
6
Remission of symptoms with removal of drug
7
Recurrence with rechallenge (rarely advisable)
8
Causality assessment
More detailed checklist
See also under
Bosutinib
2
Dasatinib
4
Nilotinib
2

Publications

Acute pulmonary complications in patients with hematologic malignancies.
Radiographics : a review publication of the Radiological Society of North America, Inc 2014 Oct;34;1755-68 2014 Oct
Challenging problems in advanced malignancy: Case 3. Imatinib mesylate-induced interstitial pneumonitis.
Journal of clinical oncology : official journal of the American Society of Clinical Oncology 2003 Aug 15;21;3171-3 2003 Aug 15

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