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The Drug-Induced Respiratory Disease Website

Philippe Camus, M.D.

Dijon, France

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Imatinib

3

II.d Pulmonary edema, cardiogenic

1
Last update : 08/04/2013
 
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Identify causative drugs
Diagnosing DIRD
1
Drug and radiation history
2
Drug singularity - Correct identification of the drug
3
Consistent timing of exposure v. onset of symptoms
4
Clinical, imaging, BAL, pathological pattern consistent with the specific drug
5
Careful exlusion of another cause
6
Remission of symptoms with removal of drug
7
Recurrence with rechallenge (rarely advisable)
8
Causality assessment
More detailed checklist
See also under
Bosutinib
2
Dasatinib
4
Nilotinib
2

Publications

Congestive heart failure in a 77-year-old woman receiving adjuvant treatment with imatinib for a large gastric gastrointestinal stromal tumour.
Anti-cancer drugs 2012 Jun;23 Suppl;S15-7 2012 Jun
Imatinib-induced decompensated heart failure in an elderly patient with chronic myeloid leukemia: case report and literature review.
Journal of geriatric cardiology : JGC 2012 Dec;9;411-4 2012 Dec

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