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The Drug-Induced Respiratory Disease Website

Philippe Camus, M.D.

Dijon, France

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Zomepirac

1

IV.a Bronchospasm - Wheezing - Asthma

1
Last update : 20/01/2012
 
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Identify causative drugs
Diagnosing DIRD
1
Drug and radiation history
2
Drug singularity - Correct identification of the drug
3
Consistent timing of exposure v. onset of symptoms
4
Clinical, imaging, BAL, pathological pattern consistent with the specific drug
5
Careful exlusion of another cause
6
Remission of symptoms with removal of drug
7
Recurrence with rechallenge (rarely advisable)
8
Causality assessment
More detailed checklist

Publications

The effect of indication on hypersensitivity reactions associated with zomepirac sodium and other nonsteroidal antiinflammatory drugs.
Arthritis and rheumatism 1987 Oct;30;1142-8 1987 Oct
Zomepirac sodium (Zomax) hypersensitivity in aspirin-sensitive asthmatics.
The American review of respiratory disease 1984 Dec;130;1170-3 1984 Dec

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