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The Drug-Induced Respiratory Disease Website

Philippe Camus, M.D.

Dijon, France

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Vinorelbine

1

IV.a Bronchospasm - Wheezing - Asthma

1
Last update : 14/09/2012
 
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Identify causative drugs
Diagnosing DIRD
1
Drug and radiation history
2
Drug singularity - Correct identification of the drug
3
Consistent timing of exposure v. onset of symptoms
4
Clinical, imaging, BAL, pathological pattern consistent with the specific drug
5
Careful exlusion of another cause
6
Remission of symptoms with removal of drug
7
Recurrence with rechallenge (rarely advisable)
8
Causality assessment
More detailed checklist

Publications

A case report of vinorelbine monotherapy-related acute bronchospasm and non-ST elevation acute coronary syndrome.
Tennessee medicine : journal of the Tennessee Medical Association 2011 Jan;104;47-8 2011 Jan
A summary of vinorelbine (Navelbine) safety data from North American clinical trials.
Seminars in oncology 1994 Oct;21;42-6; discussion 46-7 1994 Oct

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