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The Drug-Induced Respiratory Disease Website

Philippe Camus, M.D.

Dijon, France

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Venlafaxine

2

XII.f Cardiomyopathy (acute, subacute, chronic)

1
Last update : 08/08/2012
 
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Identify causative drugs
Diagnosing DIRD
1
Drug and radiation history
2
Drug singularity - Correct identification of the drug
3
Consistent timing of exposure v. onset of symptoms
4
Clinical, imaging, BAL, pathological pattern consistent with the specific drug
5
Careful exlusion of another cause
6
Remission of symptoms with removal of drug
7
Recurrence with rechallenge (rarely advisable)
8
Causality assessment
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Publications

Simultaneous interstitial pneumonitis and cardiomyopathy induced by venlafaxine.
Jornal brasileiro de pneumologia : publicacao oficial da Sociedade Brasileira de Pneumologia e Tisilogia 2014;40;313-8 2014
Fatal cardiotoxicity induced by venlafaxine overdosage.
Clinical toxicology (Philadelphia, Pa.) 2008 Apr;46;336-7 2008 Apr
Drug-induced pneumonitis and heart failure simultaneously associated with venlafaxine.
American journal of respiratory and critical care medicine 2003 Apr 01;167;958-61 2003 Apr 01
A depressed myocardium.
Journal of toxicology. Clinical toxicology 2000;38;453-5 2000

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