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The Drug-Induced Respiratory Disease Website

Philippe Camus, M.D.

Dijon, France

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Valproate (Valproic acid)

2

V.m Pleuropericarditis - Pleuropericardial effusion (ANA unknown or negative)

1
Last update : 14/09/2012
 
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Diagnosing DIRD
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Drug and radiation history
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Drug singularity - Correct identification of the drug
3
Consistent timing of exposure v. onset of symptoms
4
Clinical, imaging, BAL, pathological pattern consistent with the specific drug
5
Careful exlusion of another cause
6
Remission of symptoms with removal of drug
7
Recurrence with rechallenge (rarely advisable)
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Causality assessment
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See also under
Anticonvulsants
3
Divalproate (sodium)
1

Publications

Valproic acid associated pleuropericardial effusion: case report.
Ideggyogyaszati szemle 2020 Jan 30;73;70-72 2020 Jan 30
[Febrile pleuropericarditis during valproic acid treatment].
Presse medicale (Paris, France : 1983) 2001 Jan 20;30;62-3 2001 Jan 20

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