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The Drug-Induced Respiratory Disease Website

Philippe Camus, M.D.

Dijon, France

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Acebutolol

2

X.y Subclinical ANA positivity

1
Last update : 20/12/2013
 
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Identify causative drugs
Diagnosing DIRD
1
Drug and radiation history
2
Drug singularity - Correct identification of the drug
3
Consistent timing of exposure v. onset of symptoms
4
Clinical, imaging, BAL, pathological pattern consistent with the specific drug
5
Careful exlusion of another cause
6
Remission of symptoms with removal of drug
7
Recurrence with rechallenge (rarely advisable)
8
Causality assessment
More detailed checklist
See also under
Beta-blockers
5

Publications

Adverse effects of acebutolol in chronic stable angina: drug-induced positive antinuclear antibody.
Journal of cardiovascular pharmacology 1984;6;735-8 1984
Beta-adrenergic-receptor blockers and antinuclear antibodies in hypertension.
Clinical pharmacology and therapeutics 1982 May;31;555-8 1982 May
Antinuclear antibodies in patients on acebutolol.
British journal of clinical pharmacology 1980 May;9;515-7 1980 May

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