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The Drug-Induced Respiratory Disease Website

Philippe Camus, M.D.

Dijon, France

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Sulfasalazine

3

X.d Lupus - Lupus syndrome (see also Vd)

2
Last update : 19/01/2013
 
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Identify causative drugs
Diagnosing DIRD
1
Drug and radiation history
2
Drug singularity - Correct identification of the drug
3
Consistent timing of exposure v. onset of symptoms
4
Clinical, imaging, BAL, pathological pattern consistent with the specific drug
5
Careful exlusion of another cause
6
Remission of symptoms with removal of drug
7
Recurrence with rechallenge (rarely advisable)
8
Causality assessment
More detailed checklist
See also under
Sulfamides - Sulfonamides
3

Publications

Inflammatory bowel disease and lupus: a systematic review of the literature.
Journal of Crohn's & colitis 2012 Aug;6;735-42 2012 Aug
Sulfasalazine induced lupus in rheumatoid arthritis.
The Journal of rheumatology 1994 Apr;21;750-1 1994 Apr
Sulfasalazine-induced lupus erythematosus.
The American journal of medicine 1988 Mar;84;535-8 1988 Mar

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