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The Drug-Induced Respiratory Disease Website

Philippe Camus, M.D.

Dijon, France

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Sulfasalazine

3

XV.c Path: Organizing pneumonia (OP/BOOP) pattern (see also Id)

1
Last update : 07/10/2012
 
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Identify causative drugs
Diagnosing DIRD
1
Drug and radiation history
2
Drug singularity - Correct identification of the drug
3
Consistent timing of exposure v. onset of symptoms
4
Clinical, imaging, BAL, pathological pattern consistent with the specific drug
5
Careful exlusion of another cause
6
Remission of symptoms with removal of drug
7
Recurrence with rechallenge (rarely advisable)
8
Causality assessment
More detailed checklist
See also under
Sulfamides - Sulfonamides
3

Publications

Bronchiolitis obliterans organizing pneumonia associated with sulfasalazine in a patient with rheumatoid arthritis.
Clinical rheumatology 2004 Jun;23;249-51 2004 Jun
The lung in inflammatory bowel disease.
Medicine 1993 May;72;151-83 1993 May

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