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The Drug-Induced Respiratory Disease Website

Philippe Camus, M.D.

Dijon, France

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Sulfasalazine

3

I.a Pneumonitis (ILD), acute and/or severe (may cause ARDS)

1
Last update : 10/09/2012
 
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Identify causative drugs
Diagnosing DIRD
1
Drug and radiation history
2
Drug singularity - Correct identification of the drug
3
Consistent timing of exposure v. onset of symptoms
4
Clinical, imaging, BAL, pathological pattern consistent with the specific drug
5
Careful exlusion of another cause
6
Remission of symptoms with removal of drug
7
Recurrence with rechallenge (rarely advisable)
8
Causality assessment
More detailed checklist
See also under
Sulfamides - Sulfonamides
3

Publications

[Mesalazine and sulphasalazine for Crohn's disease: few indications, severe adverse reactions].
Nederlands tijdschrift voor geneeskunde 2011;155;A3842 2011
Sulfasalazine-induced pulmonary disease.
Chest 1992 Apr;101;1033-7 1992 Apr

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