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The Drug-Induced Respiratory Disease Website

Philippe Camus, M.D.

Dijon, France

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Sulfamides - Sulfonamides

3

I.c Eosinophilic pneumonia (pulmonary infiltrates and eosinophilia)

2
Last update : 14/09/2012
 
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Identify causative drugs
Diagnosing DIRD
1
Drug and radiation history
2
Drug singularity - Correct identification of the drug
3
Consistent timing of exposure v. onset of symptoms
4
Clinical, imaging, BAL, pathological pattern consistent with the specific drug
5
Careful exlusion of another cause
6
Remission of symptoms with removal of drug
7
Recurrence with rechallenge (rarely advisable)
8
Causality assessment
More detailed checklist
See also under
Sulfacetamide
1
Sulfadiazine
1
Sulfadoxine
1
Sulfamethoxypyridazine
1
Sulfasalazine
3
Trimethoprim sulfamethoxazole (TMP-SMX)
3

Publications

Sulfonamide-induced acute eosinophilic pneumonia requiring extracorporeal membrane oxygenation support: a case report.
Critical care science 2023;35;239-242 2023
Sulphasalazine and lung toxicity.
The European respiratory journal 2002 Apr;19;756-64 2002 Apr
Pulmonary infiltration and eosinophilia associated with sulfasalazine therapy for ulcerative colitis: a case report and review of literature.
Internal medicine (Tokyo, Japan) 1992 Jan;31;108-13 1992 Jan
[Labile infiltrate induced by a long-acting sulfonamide].
Marseille medical 1969;106;891-3 1969
Migratory pneumonia with eosinophilia associated with sulfonamide administration.
Archives of internal medicine 1967 Jul;120;85-9 1967 Jul
Interstitial Myocarditis Following the Clinical and Experimental Use of Sulfonamide Drugs.
The American journal of pathology 1942 Jan;18;109-21 1942 Jan

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