Pneumotox » Drug » Corticosteroids, systemic (oral, parenteral) » IX.a - Diaphragm/inspiratory muscle weakness/paralysis (w/wo ARF)

Corticosteroids, systemic (oral, parenteral)

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IX.a Diaphragm/inspiratory muscle weakness/paralysis (w/wo ARF)

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Last update : 10/08/2012

Diagnosing DIRD

1

Drug and radiation history

2

Drug singularity - Correct identification of the drug

3

Consistent timing of exposure v. onset of symptoms

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Clinical, imaging, BAL, pathological pattern consistent with the specific drug

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Careful exlusion of another cause

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Remission of symptoms with removal of drug

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Recurrence with rechallenge (rarely advisable)

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Causality assessment

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