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The Drug-Induced Respiratory Disease Website

Philippe Camus, M.D.

Dijon, France

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Corticosteroids, systemic (oral, parenteral)

5

X.n Tumor lysis syndrome (TLS)

1
Last update : 14/10/2015
 
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Identify causative drugs
Diagnosing DIRD
1
Drug and radiation history
2
Drug singularity - Correct identification of the drug
3
Consistent timing of exposure v. onset of symptoms
4
Clinical, imaging, BAL, pathological pattern consistent with the specific drug
5
Careful exlusion of another cause
6
Remission of symptoms with removal of drug
7
Recurrence with rechallenge (rarely advisable)
8
Causality assessment
More detailed checklist
See also under
Adrenocorticotropic hormone (ACTH)
2
Budesonide (p.o.)
1
Corticosteroids, inhaled (ICS)
5
Methylprednisolone
2
Prednisone
5
Salt (NaCl)
1

Publications

[Tumor lysis syndrome after the administration of corticosteroids in an adolescent without confirmed neoplastic disease. Case Reports].
Archivos argentinos de pediatria 2022 Feb;120;e49-e53 2022 Feb
[Tumor lysis syndrome in the course of acute lymphoblastic leukemia as the consequence of prednisone monotherapy].
Polski merkuriusz lekarski : organ Polskiego Towarzystwa Lekarskiego 2003 Aug;15;182-4 2003 Aug
[Acute tumor lysis syndrome due to mono-therapy with a corticosteroid in a patient with non-Hodgkin lymphoma].
Nederlands tijdschrift voor geneeskunde 1997 Aug 16;141;1621-3 1997 Aug 16

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