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The Drug-Induced Respiratory Disease Website

Philippe Camus, M.D.

Dijon, France

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Corticosteroids, systemic (oral, parenteral)

5

XI.ag Vertebral compression fracture

4
Last update : 22/11/2014
 
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Identify causative drugs
Diagnosing DIRD
1
Drug and radiation history
2
Drug singularity - Correct identification of the drug
3
Consistent timing of exposure v. onset of symptoms
4
Clinical, imaging, BAL, pathological pattern consistent with the specific drug
5
Careful exlusion of another cause
6
Remission of symptoms with removal of drug
7
Recurrence with rechallenge (rarely advisable)
8
Causality assessment
More detailed checklist
See also under
Adrenocorticotropic hormone (ACTH)
2
Budesonide (p.o.)
1
Corticosteroids, inhaled (ICS)
5
Methylprednisolone
2
Prednisone
5
Salt (NaCl)
1

Publications

Glucocorticoid Exposure and Fracture Risk in a Cohort of US Patients With Selected Conditions.
Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research 2018 Oct;33;1881-1888 2018 Oct
Reduced Bone Density and Vertebral Fractures in Smokers. Men and COPD Patients at Increased Risk.
Annals of the American Thoracic Society 2015 May;12;648-56 2015 May
Relationship of lung function to severity of osteoporosis in women.
The American review of respiratory disease 1990 Jan;141;68-71 1990 Jan

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