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The Drug-Induced Respiratory Disease Website

Philippe Camus, M.D.

Dijon, France

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Corticosteroids, systemic (oral, parenteral)

5

XVII.a Respiratory tract infection incl. pneumonia

1
Last update : 19/12/2013
 
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Identify causative drugs
Diagnosing DIRD
1
Drug and radiation history
2
Drug singularity - Correct identification of the drug
3
Consistent timing of exposure v. onset of symptoms
4
Clinical, imaging, BAL, pathological pattern consistent with the specific drug
5
Careful exlusion of another cause
6
Remission of symptoms with removal of drug
7
Recurrence with rechallenge (rarely advisable)
8
Causality assessment
More detailed checklist
See also under
Adrenocorticotropic hormone (ACTH)
2
Budesonide (p.o.)
1
Corticosteroids, inhaled (ICS)
5
Methylprednisolone
2
Prednisone
5
Salt (NaCl)
1

Publications

Association of Oral Corticosteroid Bursts With Severe Adverse Events in Children.
JAMA pediatrics 2021 Jul 01;175;723-729 2021 Jul 01
Adverse outcomes from initiation of systemic corticosteroids for asthma: long-term observational study.
Journal of asthma and allergy 2018;11;193-204 2018
Inhaled corticosteroids in COPD and the risk of serious pneumonia.
Thorax 2013 Nov;68;1029-36 2013 Nov
Inhaled corticosteroids and the risk of pneumonia in people with asthma: a case-control study.
Chest 2013 Dec;144;1788-1794 2013 Dec

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