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The Drug-Induced Respiratory Disease Website

Philippe Camus, M.D.

Dijon, France

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Corticosteroids, systemic (oral, parenteral)

5

XII.v Hypertrophic cardiomyopathy

2
Last update : 05/12/2013
 
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Identify causative drugs
Diagnosing DIRD
1
Drug and radiation history
2
Drug singularity - Correct identification of the drug
3
Consistent timing of exposure v. onset of symptoms
4
Clinical, imaging, BAL, pathological pattern consistent with the specific drug
5
Careful exlusion of another cause
6
Remission of symptoms with removal of drug
7
Recurrence with rechallenge (rarely advisable)
8
Causality assessment
More detailed checklist
See also under
Adrenocorticotropic hormone (ACTH)
2
Budesonide (p.o.)
1
Corticosteroids, inhaled (ICS)
5
Methylprednisolone
2
Prednisone
5
Salt (NaCl)
1

Publications

Non-neurological, steroid-related adverse events in very low birth weight infants: a prospective audit.
Swiss medical weekly 2014;144;w13954 2014
Hydrocortisone induced hypertrophic cardiomyopathy.
International journal of cardiology 2011 Aug 04;150;e94-5 2011 Aug 04
Biomarkers of corticosteroid-induced hypertrophic cardiomyopathy in preterm babies.
Frontiers in bioscience (Elite edition) 2010 Jun 01;2;1460-71 2010 Jun 01
[Glucocorticoid-induced hypertrophic cardiomyopathy in premature infants: apropos of 4 cases].
Archives de pediatrie : organe officiel de la Societe francaise de pediatrie 1997 Feb;4;152-7 1997 Feb
Iatrogenic neonatal hypertrophic cardiomyopathy.
Pediatric cardiology 1996;17;335-9 1996

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