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The Drug-Induced Respiratory Disease Website

Philippe Camus, M.D.

Dijon, France

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Sirolimus

4

XV.ac Path: Pulmonary vasculitis other than capillaritis

1
Last update : 07/04/2013
 
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Identify causative drugs
Diagnosing DIRD
1
Drug and radiation history
2
Drug singularity - Correct identification of the drug
3
Consistent timing of exposure v. onset of symptoms
4
Clinical, imaging, BAL, pathological pattern consistent with the specific drug
5
Careful exlusion of another cause
6
Remission of symptoms with removal of drug
7
Recurrence with rechallenge (rarely advisable)
8
Causality assessment
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See also under
MTOR inhibitors
5

Publications

Patterns of pulmonary complications associated with sirolimus.
Respiration; international review of thoracic diseases 2006;73;367-74 2006

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