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The Drug-Induced Respiratory Disease Website

Philippe Camus, M.D.

Dijon, France

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Simvastatin

2

I.d Organizing pneumonia pattern (an area or areas of consolidation on imaging)

1
Last update : 13/09/2012
 
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Identify causative drugs
Diagnosing DIRD
1
Drug and radiation history
2
Drug singularity - Correct identification of the drug
3
Consistent timing of exposure v. onset of symptoms
4
Clinical, imaging, BAL, pathological pattern consistent with the specific drug
5
Careful exlusion of another cause
6
Remission of symptoms with removal of drug
7
Recurrence with rechallenge (rarely advisable)
8
Causality assessment
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See also under
Statins
4

Publications

Severe acute fibrinous and organizing pneumonia (AFOP) causing ventilatory failure: successful treatment with mycophenolate mofetil and corticosteroids.
Respiratory medicine 2009 Nov;103;1764-7 2009 Nov

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