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The Drug-Induced Respiratory Disease Website

Philippe Camus, M.D.

Dijon, France

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Serrapeptase

1

I.c Eosinophilic pneumonia (pulmonary infiltrates and eosinophilia)

1
Last update : 20/01/2012
 
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Identify causative drugs
Diagnosing DIRD
1
Drug and radiation history
2
Drug singularity - Correct identification of the drug
3
Consistent timing of exposure v. onset of symptoms
4
Clinical, imaging, BAL, pathological pattern consistent with the specific drug
5
Careful exlusion of another cause
6
Remission of symptoms with removal of drug
7
Recurrence with rechallenge (rarely advisable)
8
Causality assessment
More detailed checklist

Publications

[Serrapeptase-induced lung injury manifesting as acute eosiniphilic pneumonia].
Nihon Kokyuki Gakkai zasshi = the journal of the Japanese Respiratory Society 2000 Jul;38;540-4 2000 Jul
[A case of Pulmonary infiltration with eosinophilia syndrome induced by serrapeptase].
Nihon Naika Gakkai zasshi. The Journal of the Japanese Society of Internal Medicine 1992 Nov 10;81;1865-6 1992 Nov 10

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