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The Drug-Induced Respiratory Disease Website

Philippe Camus, M.D.

Dijon, France

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Salbutamol - Albuterol

3

IV.a Bronchospasm - Wheezing - Asthma

2
Last update : 02/09/2013
 
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Identify causative drugs
Diagnosing DIRD
1
Drug and radiation history
2
Drug singularity - Correct identification of the drug
3
Consistent timing of exposure v. onset of symptoms
4
Clinical, imaging, BAL, pathological pattern consistent with the specific drug
5
Careful exlusion of another cause
6
Remission of symptoms with removal of drug
7
Recurrence with rechallenge (rarely advisable)
8
Causality assessment
More detailed checklist

Publications

Paradoxical Bronchoconstriction with Short-Acting Beta Agonist.
The American journal of case reports 2018 Oct 09;19;1204-1207 2018 Oct 09
Prevalence of paradoxical bronchoconstriction after inhaled albuterol.
Respiratory medicine 2018 Aug;141;100-102 2018 Aug
Paradoxical bronchoconstriction in asthmatic patients after salmeterol by metered dose inhaler.
BMJ (Clinical research ed.) 1992 Oct 17;305;931-2 1992 Oct 17

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