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The Drug-Induced Respiratory Disease Website

Philippe Camus, M.D.

Dijon, France

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Rituximab

5

X.ao Flare of preexisting vasculitis

1
Last update : 28/03/2020
 
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Identify causative drugs
Diagnosing DIRD
1
Drug and radiation history
2
Drug singularity - Correct identification of the drug
3
Consistent timing of exposure v. onset of symptoms
4
Clinical, imaging, BAL, pathological pattern consistent with the specific drug
5
Careful exlusion of another cause
6
Remission of symptoms with removal of drug
7
Recurrence with rechallenge (rarely advisable)
8
Causality assessment
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See also under
Anti-CD20 antibody therapy
4

Publications

Rituximab-associated Vasculitis Flare: Incidence, Predictors, and Outcome.
The Journal of rheumatology 2020 Jun 01;47;896-902 2020 Jun 01

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