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The Drug-Induced Respiratory Disease Website

Philippe Camus, M.D.

Dijon, France

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Rifampicin

1

II.b ARDS - Acute lung injury

1
Last update : 13/09/2012
 
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Identify causative drugs
Diagnosing DIRD
1
Drug and radiation history
2
Drug singularity - Correct identification of the drug
3
Consistent timing of exposure v. onset of symptoms
4
Clinical, imaging, BAL, pathological pattern consistent with the specific drug
5
Careful exlusion of another cause
6
Remission of symptoms with removal of drug
7
Recurrence with rechallenge (rarely advisable)
8
Causality assessment
More detailed checklist

Publications

Rifampicin-Induced Pneumonitis Mimicking Severe COVID-19 Pneumonia Infection.
The American journal of case reports 2020 Aug 25;21;e927586 2020 Aug 25
Acute respiratory distress syndrome induced by rifampicin with high levels of neutrophil and eosinophil products in bronchoalveolar lavage fluid.
Respiration; international review of thoracic diseases 2003;70;541-3 2003

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