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The Drug-Induced Respiratory Disease Website

Philippe Camus, M.D.

Dijon, France

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Raltitrexed

1

X.q Systemic inflammatory response

1
Last update : 13/09/2012
 
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Identify causative drugs
Diagnosing DIRD
1
Drug and radiation history
2
Drug singularity - Correct identification of the drug
3
Consistent timing of exposure v. onset of symptoms
4
Clinical, imaging, BAL, pathological pattern consistent with the specific drug
5
Careful exlusion of another cause
6
Remission of symptoms with removal of drug
7
Recurrence with rechallenge (rarely advisable)
8
Causality assessment
More detailed checklist

Publications

Raltitrexed treatment promotes systemic inflammatory reaction in patients with colorectal carcinoma.
British journal of cancer 2002 Sep 09;87;591-9 2002 Sep 09

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