Pneumotox » Drug » Radiation therapy (early effects) » XVI.bl - Imaging: An area or areas of avid tracer uptake in the lung/chest on 18F-PET scan

Radiation therapy (early effects)

XVI.bl Imaging: An area or areas of avid tracer uptake in the lung/chest on 18F-PET scan

Avidity for the tracer typically decreases with time since radiation therapy (PMID 30317847). This helps separating the radiation-induced avidity from relapse of the underlying malignant condition

Last update : 16/10/2018

Diagnosing DIRD

Drug and radiation history

Drug singularity - Correct identification of the drug

Consistent timing of exposure v. onset of symptoms

Clinical, imaging, BAL, pathological pattern consistent with the specific drug

Careful exlusion of another cause

Remission of symptoms with removal of drug

Recurrence with rechallenge (rarely advisable)

Causality assessment

More detailed checklist

The Drug-Induced Respiratory Disease Website

Philippe Camus, M.D.

Dijon, France

Radiation therapy (early effects)

XVI.bl Imaging: An area or areas of avid tracer uptake in the lung/chest on 18F-PET scan

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