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The Drug-Induced Respiratory Disease Website

Philippe Camus, M.D.

Dijon, France

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Quinidine

2

X.d Lupus - Lupus syndrome (see also Vd)

1
Last update : 08/09/2012
 
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Identify causative drugs
Diagnosing DIRD
1
Drug and radiation history
2
Drug singularity - Correct identification of the drug
3
Consistent timing of exposure v. onset of symptoms
4
Clinical, imaging, BAL, pathological pattern consistent with the specific drug
5
Careful exlusion of another cause
6
Remission of symptoms with removal of drug
7
Recurrence with rechallenge (rarely advisable)
8
Causality assessment
More detailed checklist
See also under
Quinine
3

Publications

Drug-induced lupus erythematosus: incidence, management and prevention.
Drug safety 2011 May 01;34;357-74 2011 May 01
Quinidine-induced rheumatic syndromes.
Seminars in arthritis and rheumatism 1995 Apr;24;315-22 1995 Apr
Quinidine-induced lupus erythematosus.
Annals of internal medicine 1984 Jun;100;840-2 1984 Jun
Drug induced systemic lupus erythematosus due to quinidine.
Connecticut medicine 1972 Feb;36;84-5 1972 Feb

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