Pneumotox Online
v2.2
  • RSS Feed
  • Contact
  • News
  • Diagnosing DIRD
  • Browse
  • Available on AppStore Available on AppStore

The Drug-Induced Respiratory Disease Website

Philippe Camus, M.D.

Dijon, France

  • Home
  • Browse by »
  • Drugs
  • Patterns

Protamine

2

VI.l Acute pulmonary vasoconstriction and PHT

2
Last update : 27/08/2012
 
Search
Advanced search
Identify causative drugs
Diagnosing DIRD
1
Drug and radiation history
2
Drug singularity - Correct identification of the drug
3
Consistent timing of exposure v. onset of symptoms
4
Clinical, imaging, BAL, pathological pattern consistent with the specific drug
5
Careful exlusion of another cause
6
Remission of symptoms with removal of drug
7
Recurrence with rechallenge (rarely advisable)
8
Causality assessment
More detailed checklist

Publications

A case of catastrophic pulmonary vasoconstriction after protamine administration in cardiac surgery: role of intraoperative transesophageal echocardiography.
Journal of cardiothoracic and vascular anesthesia 2008 Oct;22;727-31 2008 Oct
The use of nitric oxide for managing catastrophic pulmonary vasoconstriction arising from protamine administration.
Anesthesia and analgesia 1999 Mar;88;505-7 1999 Mar
Protamine reactions, explosive mediator release, and pulmonary vasoconstriction.
Anesthesiology 1990 Sep;73;373-5 1990 Sep
Catastrophic pulmonary vasoconstriction associated with protamine reversal of heparin.
Anesthesiology 1983 Nov;59;470-3 1983 Nov

Powered by

  • ^
  • Contact
  • Cookies
  • About