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The Drug-Induced Respiratory Disease Website

Philippe Camus, M.D.

Dijon, France

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Prostaglandin F2-alpha

1

IV.a Bronchospasm - Wheezing - Asthma

1
Last update : 20/01/2012
 
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Identify causative drugs
Diagnosing DIRD
1
Drug and radiation history
2
Drug singularity - Correct identification of the drug
3
Consistent timing of exposure v. onset of symptoms
4
Clinical, imaging, BAL, pathological pattern consistent with the specific drug
5
Careful exlusion of another cause
6
Remission of symptoms with removal of drug
7
Recurrence with rechallenge (rarely advisable)
8
Causality assessment
More detailed checklist
See also under
Prostaglandins
1

Publications

Bronchospasm after intramuscular 15-methyl prostaglandin F2 alpha and endotracheal intubation in a nonasthmatic patient.
Anesthesia and analgesia 1991 Jul;73;87-9 1991 Jul
Bronchospasm complicating intravenous prostaglandin F 2a for therapeutic abortion.
Obstetrics and gynecology 1972 Jun;39;892-6 1972 Jun

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