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The Drug-Induced Respiratory Disease Website

Philippe Camus, M.D.

Dijon, France

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Propylthiouracil (PTU)

4

I.c Eosinophilic pneumonia (pulmonary infiltrates and eosinophilia)

1
Last update : 30/08/2012
 
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Identify causative drugs
Diagnosing DIRD
1
Drug and radiation history
2
Drug singularity - Correct identification of the drug
3
Consistent timing of exposure v. onset of symptoms
4
Clinical, imaging, BAL, pathological pattern consistent with the specific drug
5
Careful exlusion of another cause
6
Remission of symptoms with removal of drug
7
Recurrence with rechallenge (rarely advisable)
8
Causality assessment
More detailed checklist

Publications

[Purpura lesions and alveolar infiltrates: propylthiouracil-induced vasculitis].
Anales de pediatria (Barcelona, Spain : 2003) 2009 Mar;70;315-7 2009 Mar
Churg-Strauss Syndrome following PTU Treatment.
International journal of rheumatology 2009;2009;504105 2009

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