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The Drug-Induced Respiratory Disease Website

Philippe Camus, M.D.

Dijon, France

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Propoxyphene

1

II.a Pulmonary edema, noncardiogenic (NCPE)

1
Last update : 20/01/2012
 
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Identify causative drugs
Diagnosing DIRD
1
Drug and radiation history
2
Drug singularity - Correct identification of the drug
3
Consistent timing of exposure v. onset of symptoms
4
Clinical, imaging, BAL, pathological pattern consistent with the specific drug
5
Careful exlusion of another cause
6
Remission of symptoms with removal of drug
7
Recurrence with rechallenge (rarely advisable)
8
Causality assessment
More detailed checklist

Publications

Pulmonary edema and disseminated intravascular coagulation after intravenous abuse of d-propoxyphene (darvon).
Southern medical journal 1972 Apr;65;493-5 1972 Apr
Pulmonary edema and propoxyphene.
JAMA 1971 Mar 29;215;2115 1971 Mar 29
Pulmonary edema associated with propoxyphene intoxication.
JAMA 1971 Jan 11;215;259-62 1971 Jan 11

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