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The Drug-Induced Respiratory Disease Website

Philippe Camus, M.D.

Dijon, France

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Propofol

3

XII.a Left or biventricular dysfunction/failure

1
Last update : 19/04/2014
 
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Identify causative drugs
Diagnosing DIRD
1
Drug and radiation history
2
Drug singularity - Correct identification of the drug
3
Consistent timing of exposure v. onset of symptoms
4
Clinical, imaging, BAL, pathological pattern consistent with the specific drug
5
Careful exlusion of another cause
6
Remission of symptoms with removal of drug
7
Recurrence with rechallenge (rarely advisable)
8
Causality assessment
More detailed checklist
See also under
Excipients-Vehicle-Preservatives (of drugs)
5
Soybean
1

Publications

Acute Decompensated Heart Failure and Cardiogenic Shock Following Propofol Infusion: A Report and Review of Pathophysiology.
Cureus 2023 Jul;15;e41815 2023 Jul
Metabolic acidosis and fatal myocardial failure after propofol infusion in children: five case reports.
BMJ (Clinical research ed.) 1992 Sep 12;305;613-6 1992 Sep 12

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