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The Drug-Induced Respiratory Disease Website

Philippe Camus, M.D.

Dijon, France

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Practolol

3

V.c Pleural thickening - Fibrothorax

1
Last update : 31/08/2012
 
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Identify causative drugs
Diagnosing DIRD
1
Drug and radiation history
2
Drug singularity - Correct identification of the drug
3
Consistent timing of exposure v. onset of symptoms
4
Clinical, imaging, BAL, pathological pattern consistent with the specific drug
5
Careful exlusion of another cause
6
Remission of symptoms with removal of drug
7
Recurrence with rechallenge (rarely advisable)
8
Causality assessment
More detailed checklist
See also under
Beta-blockers
5

Publications

Pleural fibrosis after practolol therapy.
Thorax 1978 Dec;33;822-4 1978 Dec
Interstitial pulmonary fibrosis: a new side effect of practolol.
British medical journal 1977 Jul 30;2;297-8 1977 Jul 30
Respiratory disease associated with practolol therapy.
Lancet (London, England) 1977 Dec 17;2;1254-7 1977 Dec 17

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