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The Drug-Induced Respiratory Disease Website

Philippe Camus, M.D.

Dijon, France

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Phenylephrine

2

II.d Pulmonary edema, cardiogenic

1
Last update : 11/07/2013
 
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Identify causative drugs
Diagnosing DIRD
1
Drug and radiation history
2
Drug singularity - Correct identification of the drug
3
Consistent timing of exposure v. onset of symptoms
4
Clinical, imaging, BAL, pathological pattern consistent with the specific drug
5
Careful exlusion of another cause
6
Remission of symptoms with removal of drug
7
Recurrence with rechallenge (rarely advisable)
8
Causality assessment
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Publications

Severe hypertension and pulmonary edema associated with systemic absorption of topical phenylephrine in a child during retinal surgery.
Saudi journal of anaesthesia 2012 Jul;6;285-8 2012 Jul
[Pulmonary edema after topic phenylephrine absorption during pediatric eye surgery: case report.].
Revista brasileira de anestesiologia 2004 Dec;54;815-20 2004 Dec
Adverse systemic effects from pledgets of topical ocular phenylephrine 10%.
American journal of ophthalmology 2002 Oct;134;624-5 2002 Oct

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