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The Drug-Induced Respiratory Disease Website

Philippe Camus, M.D.

Dijon, France

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Nonsteroidal anti-inflammatory drugs (NSAIDs)

5

I.c Eosinophilic pneumonia (pulmonary infiltrates and eosinophilia)

3
Last update : 23/08/2012
 
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Identify causative drugs
Diagnosing DIRD
1
Drug and radiation history
2
Drug singularity - Correct identification of the drug
3
Consistent timing of exposure v. onset of symptoms
4
Clinical, imaging, BAL, pathological pattern consistent with the specific drug
5
Careful exlusion of another cause
6
Remission of symptoms with removal of drug
7
Recurrence with rechallenge (rarely advisable)
8
Causality assessment
More detailed checklist
See also under
Aspirin (Salicylate-ASA) - Aspirin containing drugs
5
Celecoxib
2
Diclofenac
2
Fenbufen
1
Fenoprofen
1
Ibuprofen
3
Ketoprofen
1
Ketorolac
1
Loxoprofen
1
Mefenamic acid
1
Meloxicam
1
Naproxen
2
Oxyphenbutazone
1
Phenylbutazone
2
Piroxicam
1
Pranoprofen
1
Propafenone
1

Publications

A Case of Acute Eosinophilic Pneumonia Associated With Non-steroidal Anti-inflammatory Drugs.
Cureus 2024 Jan;16;e52159 2024 Jan
Eosinophilic pneumonia induced by non-steroidal anti-inflammatory drugs: An underestimated risk.
Therapie 2018 Dec;73;473-482 2018 Dec
[Fever, pneumonia and eosinophilia].
Praxis 2007 Oct 03;96;1543-7 2007 Oct 03
Pulmonary drug toxicity: radiologic and pathologic manifestations.
Radiographics : a review publication of the Radiological Society of North America, Inc 2000;20;1245-59 2000
Piroxicam induced pulmonary infiltrates and eosinophilia.
The Journal of rheumatology 1994 Aug;21;1573-7 1994 Aug
Nonsteroidal anti-inflammatory drug-associated pulmonary infiltrates with eosinophilia. Review of the literature and Food and Drug Administration Adverse Drug Reaction reports.
Archives of internal medicine 1992 Jul;152;1521-4 1992 Jul

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