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The Drug-Induced Respiratory Disease Website

Philippe Camus, M.D.

Dijon, France

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Nitrofurantoin

5

XI.b Chest pain (acute or subacute), lone or prominent

2
Last update : 01/09/2013
 
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Identify causative drugs
Diagnosing DIRD
1
Drug and radiation history
2
Drug singularity - Correct identification of the drug
3
Consistent timing of exposure v. onset of symptoms
4
Clinical, imaging, BAL, pathological pattern consistent with the specific drug
5
Careful exlusion of another cause
6
Remission of symptoms with removal of drug
7
Recurrence with rechallenge (rarely advisable)
8
Causality assessment
More detailed checklist

Publications

Recurrent acute nitrofurantoin-induced pulmonary toxicity.
Pharmacotherapy 2006 May;26;713-8 2006 May
Dyspnea, chest pain, and cough: the lurking culprit. Nitrofurantoin-induced pulmonary toxicity.
Postgraduate medicine 2002 Jul;112;19-20, 24 2002 Jul

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