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The Drug-Induced Respiratory Disease Website

Philippe Camus, M.D.

Dijon, France

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Nitrofurantoin

5

II.a Pulmonary edema, noncardiogenic (NCPE)

1
Last update : 10/05/2012
 
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Identify causative drugs
Diagnosing DIRD
1
Drug and radiation history
2
Drug singularity - Correct identification of the drug
3
Consistent timing of exposure v. onset of symptoms
4
Clinical, imaging, BAL, pathological pattern consistent with the specific drug
5
Careful exlusion of another cause
6
Remission of symptoms with removal of drug
7
Recurrence with rechallenge (rarely advisable)
8
Causality assessment
More detailed checklist

Publications

[Nitrofurantoin-induced lung edema].
Ugeskrift for laeger 1987 Mar 23;149;851-2 1987 Mar 23
Nitrofurantoin-induced acute, subacute and chronic pulmonary reactions.
Scandinavian journal of respiratory diseases 1977;58;41-50 1977

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