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The Drug-Induced Respiratory Disease Website

Philippe Camus, M.D.

Dijon, France

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Mycophenolate mofetil

2

XVII.e Pneumocystis jiroveci pneumonia

1
Last update : 30/12/2013
 
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Identify causative drugs
Diagnosing DIRD
1
Drug and radiation history
2
Drug singularity - Correct identification of the drug
3
Consistent timing of exposure v. onset of symptoms
4
Clinical, imaging, BAL, pathological pattern consistent with the specific drug
5
Careful exlusion of another cause
6
Remission of symptoms with removal of drug
7
Recurrence with rechallenge (rarely advisable)
8
Causality assessment
More detailed checklist

Publications

Severe pneumonia in mycophenolate mofetil combined with low-dose corticosteroids-treated patients with immunoglobulin A nephropathy.
The Kaohsiung journal of medical sciences 2015 Jan;31;42-6 2015 Jan
Pneumocystis jirovecii pneumonia in mycophenolate mofetil-treated patients with connective tissue disease: analysis of 17 cases.
Rheumatology international 2014 Dec;34;1765-71 2014 Dec
Analysis of USRDS: incidence and risk factors for Pneumocystis jiroveci pneumonia.
Transplantation 2009 Jul 15;88;135-41 2009 Jul 15

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