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The Drug-Induced Respiratory Disease Website

Philippe Camus, M.D.

Dijon, France

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Metoprolol

1

IV.a Bronchospasm - Wheezing - Asthma

1
Last update : 03/09/2012
 
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Identify causative drugs
Diagnosing DIRD
1
Drug and radiation history
2
Drug singularity - Correct identification of the drug
3
Consistent timing of exposure v. onset of symptoms
4
Clinical, imaging, BAL, pathological pattern consistent with the specific drug
5
Careful exlusion of another cause
6
Remission of symptoms with removal of drug
7
Recurrence with rechallenge (rarely advisable)
8
Causality assessment
More detailed checklist
See also under
Beta-blockers
5

Publications

Respiratory tolerance of bisoprolol and metoprolol in asthmatic patients.
Journal of cardiovascular pharmacology 1986;8 Suppl 11;S69-73 1986
Asthma and beta-blockers.
European journal of clinical pharmacology 1982;22;501-9 1982

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