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The Drug-Induced Respiratory Disease Website

Philippe Camus, M.D.

Dijon, France

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Metoclopramide

1

IV.a Bronchospasm - Wheezing - Asthma

1
Last update : 20/01/2012
 
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Identify causative drugs
Diagnosing DIRD
1
Drug and radiation history
2
Drug singularity - Correct identification of the drug
3
Consistent timing of exposure v. onset of symptoms
4
Clinical, imaging, BAL, pathological pattern consistent with the specific drug
5
Careful exlusion of another cause
6
Remission of symptoms with removal of drug
7
Recurrence with rechallenge (rarely advisable)
8
Causality assessment
More detailed checklist

Publications

Occupational asthma due to metoclopramide hydrochloride (MCPH).
International journal of immunopathology and pharmacology 2001;14;145-146 2001
[A case of asthma attack induced by high-dose metoclopramide].
Gan to kagaku ryoho. Cancer & chemotherapy 1986 Sep;13;2858-60 1986 Sep
Metoclopramide and asthma.
Annals of internal medicine 1985 Nov;103;809 1985 Nov

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