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The Drug-Induced Respiratory Disease Website

Philippe Camus, M.D.

Dijon, France

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Methyldopa

2

X.d Lupus - Lupus syndrome (see also Vd)

3
Last update : 30/08/2012
 
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Identify causative drugs
Diagnosing DIRD
1
Drug and radiation history
2
Drug singularity - Correct identification of the drug
3
Consistent timing of exposure v. onset of symptoms
4
Clinical, imaging, BAL, pathological pattern consistent with the specific drug
5
Careful exlusion of another cause
6
Remission of symptoms with removal of drug
7
Recurrence with rechallenge (rarely advisable)
8
Causality assessment
More detailed checklist

Publications

Drug-induced lupus erythematosus.
Autoimmunity 2005 Nov;38;507-18 2005 Nov
68-year-old woman with dyspnea and chest pain.
Mayo Clinic proceedings 1996 May;71;485-8 1996 May
Methyldopa-induced systemic lupus erythematosus.
Arthritis and rheumatism 1989 Feb;32;205-8 1989 Feb

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