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The Drug-Induced Respiratory Disease Website

Philippe Camus, M.D.

Dijon, France

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Methotrexate

5

XVII.h Nontuberculous pulmonary mycobacterial infection/superinfection

1
Last update : 24/02/2013
 
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Identify causative drugs
Diagnosing DIRD
1
Drug and radiation history
2
Drug singularity - Correct identification of the drug
3
Consistent timing of exposure v. onset of symptoms
4
Clinical, imaging, BAL, pathological pattern consistent with the specific drug
5
Careful exlusion of another cause
6
Remission of symptoms with removal of drug
7
Recurrence with rechallenge (rarely advisable)
8
Causality assessment
More detailed checklist
See also under
DMARDs (disease-modifying antirheumatic drugs)
5
Pemetrexed
3

Publications

Pulmonary Mycobacteriosis in a Patient Receiving Chronic Methotrexate Treatment.
Archivos de bronconeumologia 2018 Apr;54;225-226 2018 Apr
Mycobacterium intracellulare Pulmonary Disease with Endobronchial Caseation in a Patient Treated with Methotrexate.
Tuberculosis and respiratory diseases 2013 Jul;75;28-31 2013 Jul
Pulmonary Mycobacterium abscessus disease in a patient receiving low-dose methotrexate for treatment of early rheumatoid arthritis.
Journal of infection and chemotherapy : official journal of the Japan Society of Chemotherapy 2013 Dec;19;1146-51 2013 Dec

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