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The Drug-Induced Respiratory Disease Website

Philippe Camus, M.D.

Dijon, France

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Mefloquine

1

I.l Diffuse alveolar damage (DAD) (see alsoo under IIb and XVf)

1
Last update : 12/05/2012
 
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Identify causative drugs
Diagnosing DIRD
1
Drug and radiation history
2
Drug singularity - Correct identification of the drug
3
Consistent timing of exposure v. onset of symptoms
4
Clinical, imaging, BAL, pathological pattern consistent with the specific drug
5
Careful exlusion of another cause
6
Remission of symptoms with removal of drug
7
Recurrence with rechallenge (rarely advisable)
8
Causality assessment
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See also under
Malaria prophylaxis
2

Publications

Pulmonary toxicity with mefloquine.
The European respiratory journal 2001 Nov;18;890-2 2001 Nov

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