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The Drug-Induced Respiratory Disease Website

Philippe Camus, M.D.

Dijon, France

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Lisinopril

5

VIII.a Angioedema (may cause UAO, asphyxia and death)

2
Last update : 20/01/2012
 
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Identify causative drugs
Diagnosing DIRD
1
Drug and radiation history
2
Drug singularity - Correct identification of the drug
3
Consistent timing of exposure v. onset of symptoms
4
Clinical, imaging, BAL, pathological pattern consistent with the specific drug
5
Careful exlusion of another cause
6
Remission of symptoms with removal of drug
7
Recurrence with rechallenge (rarely advisable)
8
Causality assessment
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Publications

Macroglossia secondary to lisinopril-induced acute angioedema.
Proceedings (Baylor University. Medical Center) 2019 Jan;32;70-72 2019 Jan
Severe Angioedema Associated With Angiotensin-Converting Enzyme Inhibitor Therapy in Two Patients With Pollen-Food Allergy Syndrome.
Journal of clinical hypertension (Greenwich, Conn.) 2015 Jun;17;493-4 2015 Jun
Angiotensin-converting Enzyme Inhibitor Angioedema Requiring Admission to an Intensive Care Unit.
The American journal of medicine 2015 Jul;128;785-9 2015 Jul
Life-threatening ACE inhibitor-induced angioedema after eleven years on lisinopril.
Journal of pharmacy practice 2013 Aug;26;382-8 2013 Aug
Isolated unilateral tongue oedema: the adverse effect of Angiotensin converting enzyme inhibitors.
Current drug safety 2012 Nov 01;7;382-3 2012 Nov 01
Antihypertensive drug-induced angioedema causing upper airway obstruction in children.
International journal of pediatric otorhinolaryngology 2012 Jan;76;14-9 2012 Jan
A case of airway compromise.
BMJ (Clinical research ed.) 2010 Sep 29;341;c3822 2010 Sep 29
Acutely swollen tongue in a middle-aged woman.
American family physician 2010 Aug 01;82;279 2010 Aug 01
ACE-I induced angioedema: a case report and review of literature.
Cases journal 2009 Jul 27;2;7181 2009 Jul 27
Tongue swelling in the recovery room: a case report and discussion of postoperative angioedema.
Journal of clinical anesthesia 2006 May;18;226-9 2006 May
Images in clinical medicine. Angioedema of the arytenoids.
The New England journal of medicine 2005 Oct 27;353;e15 2005 Oct 27
Isolated uvular angioedema associated with ACE inhibitor use.
The Journal of emergency medicine 1995;13;327-30 1995
Angioedema following the intravenous administration of metoprolol.
Chest 1994 Dec;106;1922-3 1994 Dec
Predisposition to and late onset of upper airway obstruction following angiotensin-converting enzyme inhibitor therapy.
Chest 1992 Sep;102;871-4 1992 Sep
Fatal angioedema associated with lisinopril.
The Annals of pharmacotherapy 1992 Oct;26;1245-6 1992 Oct
Angioedema related to angiotensin-converting enzyme inhibitors.
Otolaryngology--head and neck surgery : official journal of American Academy of Otolaryngology-Head and Neck Surgery 1990 Jun;102;727-31 1990 Jun
Lisinopril: a nonsulfhydryl angiotensin-converting enzyme inhibitor.
Clinical pharmacy 1988 Sep;7;659-69 1988 Sep

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