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The Drug-Induced Respiratory Disease Website

Philippe Camus, M.D.

Dijon, France

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Amitriptyline

2

II.b ARDS - Acute lung injury

2
Last update : 06/07/2012
 
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Identify causative drugs
Diagnosing DIRD
1
Drug and radiation history
2
Drug singularity - Correct identification of the drug
3
Consistent timing of exposure v. onset of symptoms
4
Clinical, imaging, BAL, pathological pattern consistent with the specific drug
5
Careful exlusion of another cause
6
Remission of symptoms with removal of drug
7
Recurrence with rechallenge (rarely advisable)
8
Causality assessment
More detailed checklist
See also under
Amitriptylline overdose
1

Publications

Adult respiratory distress syndrome associated with amitriptyline overdose.
Veterinary and human toxicology 1994 Aug;36;316-7 1994 Aug
[Acute adult respiratory distress syndrome (ARDS) in a patient with amitriptyline poisoning].
Ugeskrift for laeger 1991 Mar 11;153;793-4 1991 Mar 11
Pulmonary disease after amitriptyline overdosage.
British medical journal 1973 May 05;2;300-1 1973 May 05
Pulmonary disease after amitriptyline overdosage.
British medical journal 1973 Mar 24;1;716-7 1973 Mar 24

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