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The Drug-Induced Respiratory Disease Website

Philippe Camus, M.D.

Dijon, France

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Lutetium 177 (177Lu vipivotide tetraxetan)

1

I.a Pneumonitis (ILD), acute and/or severe (may cause ARDS)

1
Last update : 07/04/2024
 
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Identify causative drugs
Diagnosing DIRD
1
Drug and radiation history
2
Drug singularity - Correct identification of the drug
3
Consistent timing of exposure v. onset of symptoms
4
Clinical, imaging, BAL, pathological pattern consistent with the specific drug
5
Careful exlusion of another cause
6
Remission of symptoms with removal of drug
7
Recurrence with rechallenge (rarely advisable)
8
Causality assessment
More detailed checklist

Publications

Diffuse Pneumonitis after Lutetium-177-PSMA-617 Treatment in a Patient with Metastatic Castration-Resistant Prostate Cancer.
BMJ case reports 2024 Feb 23;17; 2024 Feb 23

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