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Diagnosing DIRD
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The Drug-Induced Respiratory Disease Website
Philippe Camus, M.D.
Dijon, France
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Drugs
Patterns
Lidocaine (lignocaine, xylocaine)
3
II.b
ARDS - Acute lung injury
1
Last update :
14/04/2012
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Identify causative drugs
Diagnosing DIRD
1
Drug and radiation history
2
Drug singularity - Correct identification of the drug
3
Consistent timing of exposure v. onset of symptoms
4
Clinical, imaging, BAL, pathological pattern consistent with the specific drug
5
Careful exlusion of another cause
6
Remission of symptoms with removal of drug
7
Recurrence with rechallenge (rarely advisable)
8
Causality assessment
More detailed checklist
See also under
Anesthetic agents (local, topical)
Xylocaine
Publications
Acute respiratory distress syndrome after airway anesthesia with lidocaine.
Death from ARDS and cardiovascular collapse following lidocaine administration.
[Adult respiratory distress syndrome (ARDS) after poisoning by local anesthetics].
Adult respiratory distress syndrome following administration of lidocaine.
