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The Drug-Induced Respiratory Disease Website

Philippe Camus, M.D.

Dijon, France

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Sodium nitrite (NaNO2)

1

XIV.a Methemoglobinemia

1
Last update : 23/07/2022
 
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Diagnosing DIRD
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Drug and radiation history
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Drug singularity - Correct identification of the drug
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Consistent timing of exposure v. onset of symptoms
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Clinical, imaging, BAL, pathological pattern consistent with the specific drug
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Careful exlusion of another cause
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Remission of symptoms with removal of drug
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Recurrence with rechallenge (rarely advisable)
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Causality assessment
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See also under
Nitrites - Nitrates (oral - inhaled ('Poppers'))
3

Publications

A fatal suicidal sodium nitrite ingestion determined six days after death.
Journal of forensic and legal medicine 2023 Aug;98;102576 2023 Aug
Four cases of sodium nitrite suicidal ingestion: A new trend and a relevant Forensic Pathology and Toxicology challenge.
Legal medicine (Tokyo, Japan) 2022 Nov;59;102146 2022 Nov
Suicide attempt using sodium nitrite ordered on the internet: Two case reports.
Medicine 2022 Jul 15;101;e29355 2022 Jul 15
Methemoglobinemia caused by sodium nitrite overdose.
CMAJ : Canadian Medical Association journal = journal de l'Association medicale canadienne 2022 Aug 08;194;E1066-E1067 2022 Aug 08

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