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The Drug-Induced Respiratory Disease Website

Philippe Camus, M.D.

Dijon, France

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Leuprorelin - Leuprolide

1

I.b Pneumonitis (ILD)

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Last update : 27/08/2012
 
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Identify causative drugs
Diagnosing DIRD
1
Drug and radiation history
2
Drug singularity - Correct identification of the drug
3
Consistent timing of exposure v. onset of symptoms
4
Clinical, imaging, BAL, pathological pattern consistent with the specific drug
5
Careful exlusion of another cause
6
Remission of symptoms with removal of drug
7
Recurrence with rechallenge (rarely advisable)
8
Causality assessment
More detailed checklist
See also under
Androgen deprivation therapy (Antiandrogens)
2
Triptorelin
1

Publications

Interstitial pneumonitis associated with leuprorelin acetate for a prostate cancer: A case report.
Journal of oncology pharmacy practice : official publication of the International Society of Oncology Pharmacy Practitioners 2022 Dec;28;1910-1913 2022 Dec
Interstitial pneumonitis secondary to leuprorelin acetate for prostate cancer.
Respirology case reports 2016 Apr;4;e00146 2016 Apr
Interstitial pneumonitis induced by bicalutamide and leuprorelin acetate for prostate cancer.
International journal of urology : official journal of the Japanese Urological Association 2003 Nov;10;625-6 2003 Nov
Interstitial pneumonitis related to leuprorelin acetate and flutamide.
The Journal of urology 1999 Jan;161;221 1999 Jan
Interstitial pneumonitis associated with neoadjuvant leuprolide and nilutamide for prostate cancer.
The Journal of urology 1998 Jun;159;2099 1998 Jun
[Acute respiratory distress syndrome after injection of leuprorelin].
Therapie 1995;50;587-8 1995

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