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The Drug-Induced Respiratory Disease Website

Philippe Camus, M.D.

Dijon, France

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Ketamine

2

VIII.e Laryngospasm (a.k.a. laryngismus)

1
Last update : 15/04/2012
 
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Identify causative drugs
Diagnosing DIRD
1
Drug and radiation history
2
Drug singularity - Correct identification of the drug
3
Consistent timing of exposure v. onset of symptoms
4
Clinical, imaging, BAL, pathological pattern consistent with the specific drug
5
Careful exlusion of another cause
6
Remission of symptoms with removal of drug
7
Recurrence with rechallenge (rarely advisable)
8
Causality assessment
More detailed checklist

Publications

Laryngospasm and hypoxia after intramuscular administration of ketamine to a patient in excited delirium.
Prehospital emergency care 2012;16;412-4 2012
Recurrent episodes of intractable laryngospasm followed by laryngeal and pulmonary oedema during dissociative anaesthesia with intravenous ketamine.
Indian journal of anaesthesia 2010 Jul;54;364-5 2010 Jul
Serious adverse events during procedural sedation with ketamine.
Pediatric emergency care 2009 May;25;325-8 2009 May
Recurrent episodes of intractable laryngospasm during dissociative sedation with intramuscular ketamine.
Pediatric emergency care 2006 Apr;22;247-9 2006 Apr

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