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The Drug-Induced Respiratory Disease Website

Philippe Camus, M.D.

Dijon, France

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Amiodarone

5

XVIII.p Eye-catcher: An electron-dense ('white') thyroid

1
Last update : 13/04/2018
 
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Identify causative drugs
Diagnosing DIRD
1
Drug and radiation history
2
Drug singularity - Correct identification of the drug
3
Consistent timing of exposure v. onset of symptoms
4
Clinical, imaging, BAL, pathological pattern consistent with the specific drug
5
Careful exlusion of another cause
6
Remission of symptoms with removal of drug
7
Recurrence with rechallenge (rarely advisable)
8
Causality assessment
More detailed checklist
See also under
Dronedarone
2
Excipients-Vehicle-Preservatives (of drugs)
5
Thyroid hormones (exogenous)
1

Publications

Rise and fall of thyroid radiologic density during the time course of amiodarone-induced thyrotoxicosis.
European thyroid journal 2022 Jan 01;11; 2022 Jan 01
"White Thyroid" on Unenhanced Computed Tomography in Amiodarone-Induced Thyrotoxicosis Type 2.
Thyroid : official journal of the American Thyroid Association 2018 Jun;28;769-772 2018 Jun

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