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The Drug-Induced Respiratory Disease Website

Philippe Camus, M.D.

Dijon, France

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Amiodarone

5

V.a Pleural effusion (uni- or bilateral) (can accompany DI-LDs)

2
Last update : 11/05/2012
 
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Identify causative drugs
Diagnosing DIRD
1
Drug and radiation history
2
Drug singularity - Correct identification of the drug
3
Consistent timing of exposure v. onset of symptoms
4
Clinical, imaging, BAL, pathological pattern consistent with the specific drug
5
Careful exlusion of another cause
6
Remission of symptoms with removal of drug
7
Recurrence with rechallenge (rarely advisable)
8
Causality assessment
More detailed checklist
See also under
Dronedarone
2
Excipients-Vehicle-Preservatives (of drugs)
5
Thyroid hormones (exogenous)
1

Publications

Amiodarone-induced loculated pleural effusion without pulmonary parenchymal involvement: A case report and literature review.
Journal of natural science, biology, and medicine 2017;8;130-133 2017
Amiodarone-induced pleural fluid is not always accompanied by a risk factor.
Anadolu kardiyoloji dergisi : AKD = the Anatolian journal of cardiology 2012 May;12;281-2 2012 May
Amiodarone-induced loculated pleural effusion: case report and review of the literature.
Pharmacotherapy 2010 Feb;30;218 2010 Feb
Amiodarone pulmonary toxicity presenting as bilateral exudative pleural effusions.
Chest 1987 Jul;92;179-82 1987 Jul

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